Sep 19, 2023
The broad-spectrum antimicrobial biocide polyhexamethylene biguanide (PHMB; polyhexanide) kills bacteria, fungi, parasites and certain viruses with a high therapeutic index. Kantaraja Chindera and Coll. conducted this study in which they showed how the PHMB can work.
Sep 12, 2023
Diabetes is a disease in which patients have high level of sugar in blood. 15% to 25% of people with diabetes develop a foot ulcer in their lifetime. A multidisciplinary team from Health Quality Ontario performed this study in which they evaluated standard wound care plus hyperbaric oxygen therapy results in an improvement in ulcer healing compared with standard wound care alone.
Aug 29, 2023
The treatment for diabetic ulcer wounds is a challenging. Many studies proved that MEBT/MEBO could promote ulcer wound healing in diabetic rats.
Aug 21, 2023
Diabetic foot disease is the most common cause of hospitalization for diabetes. Patients with diabetic foot have a higher risk of amputation and death, and thus it is important to standardize their diagnosis and treatment.
Jul 25, 2023
More than 150 million people worldwide suffer from diabetes, and every patient with diabetes is at risk of developing a diabetic foot ulcer (DFU). Recent studies have explored more effective wound dressings and tissue engineering techniques. Clinical studies have already documented the safety and efficacy of ADM in chronic wound healing
Jul 12, 2023
Laser therapy (LT) applications have been used for many years in the field of dentistry and oral surgery for the treatment of pain relief and wound healing. Laser therapy has been reported to increase ATP, accelerate mitosis, improve tissue repair, stimulate bone repair, normalize collagen and elastic fibril accumulation in tissue repair, stabilize fibroblast production, increase peripheral blood flow, and improve anti-inflammatory activity
Jul 4, 2023
The skin surrounding the injury is called ‘Periwound’. it can become macerated which is vulnerable to breakdown, leading to a possible increase in the size of the wound. In such a situation, ‘Periwound Skin Management’ plays an imperative role.
Efficacy of a Urinary Bladder Matrix for Treating Wound Dehiscence With Hardware Exposure in a Patient With Rheumatoid Arthritis
Jun 21, 2023
This case report explores an effective treatment modality in a medically complicated patient with wound dehiscence of the right great toe and subsequent exposure of surgical hardware, complicated by infection treated Urinary Bladder Matrix (UBM).
May 31, 2023
Oxygen delivery is a crucial element involved in wound healing and it is widely recognized that limited oxygenation can lead to a chronic nonhealing ulcer. A retrospective review comparing healing rates of diabetic foot ulcers utilizing Hyperbaric Oxygen Therapy (HBOT) or Topical Oxygen Therapy (TOT) was performed.
May 17, 2023
A wound is a break or damage in the surface of the skin and it can be accidental as well as surgical. Debridement plays an imperative role in healing a complicated injuries. There are various methods that are available and Maggot Debridement could be one of this. Maggot therapy is a type of biotherapy involving the introduction of live, disinfected maggots (fly larvae). The flies used most often for the purpose of maggot therapy are blow flies of the Calliphoridae: the blow fly species used most commonly is Lucilia sericata, the common green bottle fly.
It is an effective technique for debriding wounds that was used especially in the previous centuries.
Apr 11, 2023
Reportedly about 20% of people who visit a doctor for advice regarding a foot problem have an ingrown toenail. The most common cause of an ingrowing toenail is not cutting your toenails properly, by cutting them too short or down the sides of your toenail, and wearing shoes which are not wide enough to fit your toes in their natural position.
Mar 20, 2023
This is the presentation about the use of biosynthetic polimer from sugar cellulos for the second degree burn at the 14th Abu Dhabi wound care conference on March 2023.
Mar 8, 2023
This is my last presentation at the 14th Abu Dhabi wound care conference on March 2023. It was presented the effectiveness of the use of Heamoglobin Spray in wound care.
Human derived Acellular Dermal Matrix Grafts for Treatment of Diabetic Foot Ulcers. A Systematic Review and Meta-analysis
Feb 23, 2023
Diabetes affects more than 22 million people in the United States and Foot wounds are a common complication associated with diabetes mellitus (DM) and often impose significant economic, health, and quality of life.
Feb 20, 2023
Oxygen is a significant factor in wound healing. In normal wound healing, the wound either requires conditions of hypoxia or normal levels of oxygen (ie, normoxia). Wound healing might be delayed in extreme hyperoxia which can cause growth arrest and cell death by mitochondria apoptosis. This study clarified that 1) oxygen is needed for mitochondrial cytochrome oxidase 2) oxygen is also involved in collagen maturation, 3) hypoxia is required to start the process of wound healing, 4) superoxide ion kills bacteria, and 5) hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers, crush injuries, and soft-tissue infections could help the wound healing.
Jan 27, 2023
Injuries are considered to be acute if they are new while more than 3 or 4 weeks old wounds are chronic. TIME Wound Assessment is a unique and significant systematic approach to wound healing that involves eliminating non-viable tissue, restoring moisture balance, controlling infection, and promoting epithelial advancement. It is not a sequential process since every wound is different. The ‘TIME’ acronym, consisting of tissue debridement, infection or inflammation, moisture balance and edge effect, has assisted clinicians systematically in wound assessment and management.
Jan 13, 2023
Hyperbaric oxygen therapy (HBOT) treats patients with 100% oxygen at greater than 1.0 atmosphere (atm). This is the largest series (22 cases) in the literature of patients with frostbite treated with HBOT as an adjunct to wound care.
Pain, Psychological Comorbidities, Disability and Impaired Qualify of Life in Hidradenitis Suppurativa
Jan 3, 2023
Hidradenitits suppurativa (HS) is a chronic, painful inflammatory skin disease characterized by recurrent inflammatory nodules and abscesses. The main factors that impact quality of life (QoL) will differ for each patient, but commonly include limitation of daily activities.
Dec 12, 2022
Wound healing can be impaired by systemic factors and local factors. Dr W Cole conducted a retrospective assessment of 10 patients (N = 10) with complex lower extremity wounds treated with either advanced wound dressings (control group; n = 5) or NPWTi-d using ROCF-CC dressings (treatment group; n = 5) that was performed between June 2015 and October 2017 at Cleveland center – Ohio.
Dec 1, 2022
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that affects apocrine gland-bearing skin in the axillae, groin, and under the breasts. It is characterised by persistent or recurrent boil-like nodules and abscesses that culminate in a purulent discharge, sinuses, and scarring
Nov 10, 2022
Foot ulcers in people with DM have a serious impact on health, related with the quality of life, particularly with respect to physical functioning and role-limitations due to physical and emotional issues. Any intervention that promotes healing makes an important difference. The Cochrane review about the use of Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus make analysis about the use of it.
Oct 26, 2022
Vasculogenic ulcers (venous, arterial, and/or both) are the most common type of ulcers in the legs. De Angelis and coll conducted this study, 35 patients affected by vasculogenic chronic ulcers localized on the inferior limbs with the application of collagen dermal substitute template. followed by the autologous dermal-epidermal graft (DEG).
Oct 6, 2022
MRSA colonization increases the risk of infection, and infecting strains match colonizing strains in as many as 50–80% of cases.
Sep 13, 2022
Chronic wounds are associated with a significant increase in health care utilization and health care costs,3 increased morbidity and mortality. Can the Wounds at Risk (WAR) score help to assess the risk of infection in patients by scoring several host factors that can contribute to an increased risk for infection in wounds?
Sep 1, 2022
Chorion-amniotic membranes are widely accepted as a therapeutic option for the healing of cutaneous wounds due to their immunologically privileged status and bioactive properties.
Aug 12, 2022
Shock Waves Therapy in the Wound Healing works by triggering the regeneration potential of cells present in the body. Therefore, shockwaves have persistently proven to be an effective treatment for a wide range of painful injuries and conditions.
Aug 2, 2022
The skin wound might be of different nature and varies from surgical to accidental lacerations, burns, pressure ulcers, diabetic ulcers, and venous ulcers. Mesenchymal stromal cells, also known as mesenchymal stem cells (MSCs), are adult stem cells capable of self-renewal and multipotential differentiation. MSC transplantation led to accelerated cutaneous wound closure. the mechanisms by which these stem cells contribute to the healing process have yet to be elucidated
Jul 19, 2022
As we age, our epidermis undergoes several changes. The key characteristics of geriatric sufferers are advanced age, a decrease in physical performance, care dependency, and multimorbidity. In addition, this stage of life leads either directly or indirectly, to a wide range of skin as well as tissue problems.
Jun 28, 2022
A long-term condition that affects one of the legs or arms. In a few cases, both legs and arms may be affected.
Jun 9, 2022
Hyaluronic acid (hyaluronan, HA) is a large glycosaminoglycan and an essential extracellular component of skin It is active throughout the entire process of wound healing being involved in proliferation, migration, and tissue remodelling. Erika Nyman published on 2019 this interesting study in which he investigated the influence of exogenous HA on re-epithelialization, erythema, and protein expression. Nyman and Coll concluded that exogenous intradermal HA accelerates re-epithelialization and alters protein expression in human in vivo deep dermal skin wounds.
PRP Application prior to Resurfacing with Split Thickness Skin Graft Vs Conventional Mechanical Fixation Using Sutures and Staples
May 24, 2022
A split-thickness skin graft is generally done for soft skin coverage. The healing process is undertaken through three stages anchorage, inosculation and maturation. Subha Dhua and colleagues conducted this Randomized control study on 40 patients for 24 months from October 2015 to September 2017. The application of autologous platelet-rich plasma (PRP) to the split-thickness skin graft sites is considered and theorized to provide immediate skin graft anchorage.
May 17, 2022
Venous insufficiency is a condition that occurs when valves within the leg veins are damaged allowing blood to leak backwards and pool in these veins.
Apr 27, 2022
Thermal burn initiates systemic inflammatory reactions producing burn toxins, oxygen radicals and finally leads to peroxidation. Negative pressure wound therapy (NPWT) is a non-invasive adjuvant therapy to treat burn wounds.
Staphylococcus aureus Infections Epidemiology, Pathophysiology, Clinical Manifestations and Management
Apr 10, 2022
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. Steven Y.and coll conducted this study to summarize recent developments in the epidemiology, pathophysiology, clinical manifestations, and management of these key S. aureus clinical infection syndromes.
Mar 29, 2022
Cong Fan and colleagues conducted a retrospective review about pediatric burns patients admitted to the pediatric burns unit from January 2014 to April 2015 at Singapore General Hospital, Singapore. This study aimed to compare the results of Biobrane dressing with conventional silver foam dressing. In the Biobrane group, the length of hospital stay was significantly shorter and the infection rate was significantly lower
Mar 11, 2022
The scope is to remove the damaged and dead tissue to remove the death tissue and bacteria from the wound, minimising infection risk and encouraging healthy granulation tissue.
Feb 28, 2022
A chronic wound is an injury that doesn’t heal in six weeks. Factors that contribute to chronic wounds include increased bacterial load, inappropriate treatment, trauma, lower extremity wounds, senescent/aberrant cells and so on
Feb 21, 2022
Edema is swelling that occurs in different areas of the body when too much fluid gets trapped in the tissues. It often takes place in the epidermis, particularly on the legs, feet, ankles, arms, and hands.
Jan 17, 2022
SSI is an infection related to a surgical procedure that occurs near the surgical site within 30 days following surgery
Jan 3, 2022
Bedsores (also called pressure ulcers or decubitus ulcers) are injuries of the skin and underlying tissue, resulting from prolonged pressure on the skin. Westby MJ and Coll have successfully conducted a network meta-analysis of dressings and topical agents for healing pressure ulcers. This review includes 51 RCTs involving a total of 2964 participants, comparing 39 different dressings or topical agents for the healing of pressure ulcers.
Dec 10, 2021
Diabetes mellitus, commonly known as diabetes, is a metabolic disease that causes high blood sugar. Untreated high blood sugar from diabetes can damage your nerves, eyes, kidneys, and other organs.
Silver foam dressing and zinc-hyaluronic gel for the treatment of partial thickness hand burn injuries
Dec 1, 2021
The hydrofiber dressing consists of a superficial polyurethane waterproof layer and a multilayered absorbent surface containing 1.2% ionized silver. Zinc-hyaluronic acid promotes cell regeneration.
Gergo Jozsa conducted this study in which 37 children were treated conservatively with a special dressing at first intervention containing Hydrofiber dressing with silver foam and Zn-hyaluronic gel to determine their effectiveness on partial-thickness hand burns.
Nov 8, 2021
In the UK it has been estimated that 4% to 5% of patients undergoing a surgical procedure contract an SSI. Dumville JC and Coll conducted this review, including 29 trials (5718 participants). The scope of the work was to compare Dressings for the prevention of surgical site infection.
Sep 27, 2021
Oxygen is the basis for wound healing, and it begins at the cellular level. Smoking deprives the body of the oxygen it needs to repair wounds and build new tissue. not many people know that smoking also slows down the healing process.
Sep 14, 2021
The ‘Lymphatic System’ is a complex network of tissues & organs that play an imperative role in homeostasis of extracellular space. Patients suffering from lymphedema have increased the risk of wound formation.
Sep 1, 2021
Wound healing is a well-coordinated sequence of events in which signalling and remodelling of the extracellular matrix (ECM) are integral components. dehydrated human amnion/chorion membrane (dHACM) has demonstrated clinical efficacy in the enhancement of wound repair compared with standard compression therapy.
Comparison of Efficacy and Complications Between Negative Pressure Wound Therapy and Conventional Mechanical Fixation in Skin Grafts: A Retrospective Analysis.
Aug 4, 2021
Negative-pressure wound therapy (NPWT) is a therapeutic technique using a suction dressing to remove excess exudation and promote healing in acute or chronic wounds and second-and third-degree burns. Negative pressure could be utilized to secure a skin graft, improving the drainage. Shen X and Coll conducted this retrospective study in which they evaluated 186 patients
Jul 22, 2021
A chronic wound is an injury type that develops when an acute wound fails to heal in the expected time. It might be a couple of weeks or six weeks in a few cases. The conditions that stop or slow the healing process may lead to similar illnesses are infection, weak immune system, poor blood supply & low oxygen and so on.
Jul 12, 2021
Burns, trauma, chronic and complex wounds can result in complete loss of skin, leading to infection, increased insensible water loss, hypothermia, difficulties in patient management. Lenon Cardoso and Coll performed this study to assess the efficiency of a porous bioresorbable membrane Poly (L-co-DL lactic acid)-co-trimethylene carbonate, PL-co-DLA-co-TMC, as a dermal substitute associated with partial skin graft in rats.
Jun 23, 2021
A chronic wound is a lesion that doesn’t heal in a specific time but shows delayed wound healing. Many factors could lead an acute wound to become a chronic wound such as diabetes with its complications, low blood flow, soft tissue infection and so many other conditions.
Jun 3, 2021
It was a pleasure to be a speaker at the 6th Emirates Plastic Surgery Congress in Dubai. You could have a look at the topic ”the use of porcine urinary bladder matrix in wound care”
May 24, 2021
Silver has broad-spectrum antimicrobial properties against a wide spectrum of gram-positive and gram-negative bacteria. The use of Silver dressings is recommended for acute or chronic wounds with, or at risk of, a high level of bioburden or local infection.
Apr 29, 2021
The skin has various significant functions including prevention of loss of body water, temperature control, protection from harmful microbes & substances, and temperature control. Skin Assessment is a process in which the entire skin of a sufferer is examined for abnormalities.
Apr 6, 2021
An ingrown toenail, also known as onychocryptosis, occurs when the nail plate grows into the adjacent periungual skin and acts as a foreign body, causing inflammation and infection. Sumanth Kumar Gera conducted this study to compare the results of nonoperative treatment for IGTN with that of operative treatment among children and adolescents. This study aimed to compare the results of nonoperative treatment for IGTN with that of operative treatment among children and adolescents.
Mar 22, 2021
The approach of regenerative medicine has emerged as an alternative to provide additional therapeutic options to potentially improve wound healing.
Mar 8, 2021
Hyperbaric oxygen therapy (HBOT) delivers 100% inspired oxygen to individuals at 2.0 to 2.5 absolute atmospheres (ATA) of pressure for a typical total duration of 60-120 minutes during 1-2 daily sessions inside a hyperbaric chamber. Laura Bolton conducted a systematic review of randomized clinical trials (RCTs) comparing HBOT effects on chronic wounds to those of another therapeutic regimen.
Feb 22, 2021
Ulcers are open skin sores that can affect any area of the epidermis and they most often occur on the legs due to problems with blood circulation in the veins.
Jan 28, 2021
The dermis is the mesenchymal component of the skin, separated from the epidermis by the basement membrane. . The dermis comprises two structurally different layers named the papillary and reticular layer. Alexandra L. Rippa and Coll published this scientific article about the different steps of the wound healing and which cells are involved in the healing process.
Jan 13, 2021
A Bone Infection can result when fungi or bacteria invade a bone. It can either develop suddenly or over a long period. The first and foremost Symptom of the same is pain at the infection site.
Dec 28, 2020
Contact dermatitis is an itchy and red rash that crops up on your epidermis when you touch or have a reaction to a few substances. Contact Dermatitis is caused by a substance you are exposed to which either irritates your skin or triggers an allergic reaction.
Nov 30, 2020
A burn is tissue damage that results from scalding, overexposure to the sun or other radiation, contact with flames, chemicals or electricity, or smoke inhalation.
Nov 16, 2020
Surgical site infection (SSI) may occur in 5–20% after surgery. Up to 60% of SSI can be prevented. Bjørg Marit Andersen made an interesting scientific article about the prevention of postoperative wound infection.
Nov 2, 2020
Human amniotic membranes (hAMs) have shown promising results in recent studies aimed at improving wound healing. Ben Samuel John and Coll conducted a study on the 2019 full-thickness skin defects in 4 groups of 6 rats with one wound each.
Oct 14, 2020
Wound assessment of a wound is a breakdown in the protective function of the epidermis. If it becomes infected, it can get worsen instead of better. Bacterial Wound Colture is a test to identify harmful bacteria that may be growing in the injury. the type(s) of germ detected is afterwards subjected to sensitivity/susceptibility testing. the final outcome allows clinicians to make a wise decision about the appropriate therapy to inhibit the growth of the bacterium.
Sep 17, 2020
SSI stands for Surgical Site Infection, an infection that occurs after surgery in the part of the body where the surgery took place. About 1 to 3 out of every 100 patients develop some infection after the surgical intervention.
Sep 1, 2020
Pressure Injury is an area of the injured epidermis. It happens when force is applied to the outermost layer of the skin, especially over the bony body parts. The inadequate diet intake, low body mass index, and presence of malnutrition have been acknowledged as the pivotal risk factors for both the delayed wound recovery and development of pressure injuries. An adequate amount of right supplements could be required for these patients.
Aug 3, 2020
Etiologies of chronic diabetic foot ulcers (DFUs) are multifactorial. They are caused by angiopathy and poor skin sensation due to peripheral neuropathy.
Chou WY conducted this study at Kaohsiung Chang Gung Memorial Hospital (Kaohsiung, Taiwan). During the course of study, a total of 21 patients were screened. Extracorporeal shockwave therapy was shown to induce neovascularization and increase angiogenic and osteogenic growth factors that lead to improvement in blood flow perfusion and tissue regeneration.
Jul 22, 2020
A discussion about the causes and treatment of ingrowing nails. Have a look of my contents in the Al Das Medical Clinic web site.
Jul 8, 2020
Deep Venous Thrombosis is a condition where blood clots form in the vein deep in your body, often in your legs. Oedema, leg pain, the warmth of the skin over the area of thrombosis are the most common clinical sign and symptoms.
Jun 26, 2020
Walid Mari and Coll conducted a prospective, multicentered, randomized, controlled, single-blinded clinical trial from August 2014 to June 2016 about the use of negative pressure and natural porcine extracellular matrix in stage 4 pressure injuries.
Jun 16, 2020
A discussion about the use of dermal substitutes collagen made for the treatment of burn. Have a look of my contents in the Al Das Medical Clinic web site
Jun 1, 2020
Leg Ulcer is an open wound or a sore on the legs. they are more common in females but can affect both women and men of any age. It is necessary to have assessment before performing the bandage. Several clinical conditions could cause leg ulcers. Usually a graduated external compression plays a major role in the successful treatment for lower limb open wounds, especially for the treatment of venous ulcers.
May 21, 2020
An interesting scientific publication Reza Vaghardoost and Coll. A study was conducted in which they evaluated herbal ointment (composed of sesame oil, camphor and honey) to treat a second degree burn wound.
Apr 27, 2020
Biofilms are dynamic communities of bacterias. Biofilm in injury is a type of contamination made up of living microorganisms which are capable of forming colonies. If a patient has treated for the non-healing chronic wound which failed to progress, they are most likely dealing with a Biofilm. Topical agents including Creams, Methylene Blue, and Cadexomer iodine also help eradicate the Biofilm.
Apr 14, 2020
Only minor injuries can be treated at home through medications & natural remedies. But, in case of wounds which involve skin and subcutaneous tissues, muscular fascia or bones, you need to look for immediate medical attention.
Mar 11, 2020
With the emergence of multidrug-resistant strains of organisms and a better understanding of the dynamics of wound healing, there has been an interest in topical use of iodine in wound care.
Feb 24, 2020
Another scientific publication about a clinical case at Al Zahra Hospital Dubai, using Dehydrated human amnion/chorion membrane for the treatment of venous leg ulcers.
Feb 5, 2020
“Topical Antibiotics” are medicines in the form of cream & ointment applied directly to the skin for destroying or inhibiting the growth of susceptible bacteria. The primary role of “Topical Antibiotic” is to reduce the microbial contaminant exposure after the surgery.
Jan 27, 2020
This is my last presentation at the 5th Emirates Plastic Surgery Congress in Dubai in January 2020. Debridement as the first step for wound healing.
Jan 21, 2020
This is the second of three presentations that I had at the 5th Emirates Plastic Surgery Congress in Dubai in January 2020. It describes the use of dermal substitutes and tissue engineering in wound healing.
Jan 18, 2020
This is the first of three presentations and it describes the use of advanced dressing in the clinical practice.
Jan 7, 2020
An interesting scientific publication by Fabiana da Silva Augusto and Coll conducted single-center case series from April 2012 to July 2013, comparing the use of hydrocellular foam and hydrocolloid plate dressings on the prevention of bedsores.
Dec 8, 2019
I had my talk during 2nd Al Zahra Hyperbaric Oxygen therapy Symposium. Many thanks to Al Zahra Hospital Dubai for the opportunity and the continuous support!
Nov 24, 2019
Nutritional status of patients at the time of trauma influences the biochemical processes necessary for the phases of normal healing to occur
To heal them properly, all you need is to undergo an effective treatment method. Also, it’s pivotal to maintain healthy levels of “Vitamins” like A, B, C, E and other nutrients.
Nov 5, 2019
This is a clinical case using hADM to close an open wound of the right foot caused by the penetration of part of a shell into the skin followed by necrotizing fasciitis, after multiple unsuccessful treatments using Negative Pressure Wound Therapy, porcine acellular dermal substitutes and a split-thickness skin graft.
Oct 15, 2019
“Wound Bed Preparation” has become a standard model that allows physicians to identify and breakdown local barriers for healing the injury. It’s a complex process that can be impacted by an array of significant factors. In addition, it usually progresses through various phases…
Sep 30, 2019
Hyaluronic acid is a natural polymer. In the human body, it is distributed around cells and in the extracellular matrix (ECM). A Fallacara and Coll conducted an interesting overview, describing the history, physicochemical, structural and hydrodynamic of hyaluronic acid. They evaluated also the different applications of the HA in medicine, pharmaceutical and cosmetic fields.
Sep 12, 2019
Venous ulcers are wounds that are thought to occur due to improper functioning of venous valves, usually of the legs. They are the major occurrence of chronic wounds, occurring in 70% to 90% of leg ulcer cases. Venous ulcers develop mostly along the medial distal leg and can be painful with negative effects on quality of life.
Aug 7, 2019
Hyperbaric oxygen therapy (HBOT) is an of treatment in which a patient breathes 100% oxygen at a pressure greater than 1 atmospheric pressure (ATA) in a chamber. The aim of the treatment is to increase the O2 level dissolved in the plasma up to 15 times the normal amounts, which helps in the treatment of many diseases.
Jul 29, 2019
An interesting scientific publication by Dr. Tettelbach and Coll who conducted a prospective, randomized, controlled and multicentre clinical trial. The scope of this study was to evaluate the healing outcomes in diabetic patients with chronic lower extremity ulcers treated with a weekly application of dHACM.