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Advances of Stem Cell Therapeutics in Cutaneous Wound
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Advances of Stem Cell Therapeutics in Cutaneous Wound

The skin wound might be of different nature and varies from surgical to accidental lacerations, burns, pressure ulcers, diabetic ulcers, and venous ulcers. Mesenchymal stromal cells, also known as mesenchymal stem cells (MSCs), are adult stem cells capable of self-renewal and multipotential differentiation. MSC transplantation led to accelerated cutaneous wound closure. the mechanisms by which these stem cells contribute to the healing process have yet to be elucidated

PRP Application prior to Resurfacing with Split Thickness Skin Graft Vs Conventional Mechanical Fixation Using Sutures and Staples
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PRP Application prior to Resurfacing with Split Thickness Skin Graft Vs Conventional Mechanical Fixation Using Sutures and Staples

A split-thickness skin graft is generally done for soft skin coverage. The healing process is undertaken through three stages anchorage, inosculation and maturation. Subha Dhua and colleagues conducted this Randomized control study on 40 patients for 24 months from October 2015 to September 2017. The application of autologous platelet-rich plasma (PRP) to the split-thickness skin graft sites is considered and theorized to provide immediate skin graft anchorage.

Silver foam dressing and zinc-hyaluronic gel for the treatment of partial thickness hand burn injuries
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Silver foam dressing and zinc-hyaluronic gel for the treatment of partial thickness hand burn injuries

The hydrofiber dressing consists of a superficial polyurethane waterproof layer and a multilayered absorbent surface containing 1.2% ionized silver. Zinc-hyaluronic acid promotes cell regeneration.
Gergo Jozsa conducted this study in which 37 children were treated conservatively with a special dressing at first intervention containing Hydrofiber dressing with silver foam and Zn-hyaluronic gel to determine their effectiveness on partial-thickness hand burns.

Comparison of Efficacy and Complications Between Negative Pressure Wound Therapy and Conventional Mechanical Fixation in Skin Grafts: A Retrospective Analysis.
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Comparison of Efficacy and Complications Between Negative Pressure Wound Therapy and Conventional Mechanical Fixation in Skin Grafts: A Retrospective Analysis.

Negative-pressure wound therapy (NPWT) is a therapeutic technique using a suction dressing to remove excess exudation and promote healing in acute or chronic wounds and second-and third-degree burns. Negative pressure could be utilized to secure a skin graft, improving the drainage. Shen X and Coll conducted this retrospective study in which they evaluated 186 patients

Hyperbaric Oxygen Therapy Effects on Chronic Wounds
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Hyperbaric Oxygen Therapy Effects on Chronic Wounds

Hyperbaric oxygen therapy (HBOT) delivers 100% inspired oxygen to individuals at 2.0 to 2.5 absolute atmospheres (ATA) of pressure for a typical total duration of 60-120 minutes during 1-2 daily sessions inside a hyperbaric chamber. Laura Bolton conducted a systematic review of randomized clinical trials (RCTs) comparing HBOT effects on chronic wounds to those of another therapeutic regimen.

Bone infection: Osteomyelitis
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Bone infection: Osteomyelitis

A Bone Infection can result when fungi or bacteria invade a bone. It can either develop suddenly or over a long period. The first and foremost Symptom of the same is pain at the infection site.

The use of Extracorporeal Shockwave Therapy for Chronic Diabetic Foot Ulcers
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The use of Extracorporeal Shockwave Therapy for Chronic Diabetic Foot Ulcers

Etiologies of chronic diabetic foot ulcers (DFUs) are multifactorial. They are caused by angiopathy and poor skin sensation due to peripheral neuropathy.
Chou WY conducted this study at Kaohsiung Chang Gung Memorial Hospital (Kaohsiung, Taiwan). During the course of study, a total of 21 patients were screened. Extracorporeal shockwave therapy was shown to induce neovascularization and increase angiogenic and osteogenic growth factors that lead to improvement in blood flow perfusion and tissue regeneration.

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