The Healing Effect of Sesame Oil, Camphor and Honey on Second Degree Burn Wounds in Rat
A burn is damage to the skin caused by heat, cold, electricity, chemicals, friction or radiation. This study evaluated the healing effect of herbal ointment in the second-degree burn wound in the animal.
A second-Degree (Partial Thickness) burn affects the part of the lower layer of skin (epidermis and dermis). The patient complains pain and the skin is swollen, red and blistered.
Many studies were supported to develop more sophisticated dressings to accelerate the healing procedure and reduce the bacterial burden in wounds and even medicinal plants were presented in wound healing of burned wounds. Honey is the oldest known treatments decreasing the inflammation, oedema and exudation, promoting the healing process, stimulating tissue regeneration.
Reza Vaghardoost and Coll conducted this study in which they evaluated herbal ointment (composed of sesame oil, camphor and honey) were investigated on second-degree burn wound in the rat in comparison with vaseline. Forty rats were randomly assigned to two equal groups. The burns were dressed daily with a herbal ointment containing extract of sesame oil, camphor and honey in group 1, dressing oil vaseline in group 2. The results after the treatment were evaluated on 0, 7, 14, 21, 28 days and they showed considerable epithelization in the herbal ointment group vs the control group.
This interesting study showed that histological epithelization and neovascularization were less in vaseline group and the time of burn wound contraction was shorter in the herbal ointment one.
The herbal ointment could be considered an alternative treatment for the second-degree burn wounds.